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By Koichiro Niwa, Harald Kaemmerer

ISBN-10: 4431560696

ISBN-13: 9784431560692

ISBN-10: 4431560718

ISBN-13: 9784431560715

This is the 1st textbook to target Aortopathy, a brand new medical thought for a kind of vasculopathy. the 1st element of the e-book starts off from discussing common idea and heritage of Aortopathy, after which bargains with its pathophysiology, manifestation, intrinsic issue, medical implication, administration and prevention. the second one half heavily appears to be like at a variety of problems of the Aortopathy comparable to bicuspid aortic valve and coarctation of aorta. The booklet editors have released loads of works at the subject and feature been accumulating concerning information within the box of congenital middle disorder for the earlier two decades, therefore current the booklet with confidence.

The subject - an organization of aortic pathophysiological abnormality, aortic dilation and aorto-left ventricular interplay - is getting an increasing number of cognizance between cardiovascular physicians. this can be the 1st publication to refer for cardiologists, pediatric cardiologists, surgeons, ACHD experts, and so forth. to obtain thorough wisdom on Aortopathy.

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Example text

3 Penetrating Atherosclerotic Ulcer (PAU) In the early stages of a penetrating atherosclerotic ulcer (PAU), just the intima is ulcerated, but the process may progress further into the media, inducing a hematoma within the media [38]. The penetrating atherosclerotic ulcer can resolve, stay stable, but can also cause aortic aneurysms, aortic dissection, and even aortic rupture [39]. Penetrating aortic ulcers are located commonly in the descending aorta, where atherosclerosis is more prevalent. 1 Clinical Presentation PAU typically occurs in older individuals with generalized atherosclerosis such as coronary artery disease.

Narrowing of the coronary artery ostia may lead to myocardial ischemia and even infarction. A sluggish blood flow can predispose to atheroma, thrombus formation, and peripheral embolization. 3 Acute Aortic Syndrome (AAS) For the identification of patients at risk for acute aortic syndrome (AAS), the early clinical detection of aortopathies is of outstanding importance. Only timely discovery provides the chance to induce prophylactic or therapeutic measures. Pain is the central feature of an AAS which comprises aortic dissection (AD), intramural hematoma (IMH), and penetrating atherosclerotic ulcer (PAU) (Fig.

Natelson EA, Watts HD, Fred HL (1970) Cystic medionecrosis of the pulmonary arteries. Chest 57:333–335 44. Hankins GDV, Brekken AL, Davis LM (1985) Maternal death secondary to a dissecting aneurysm of the pulmonary artery. Obstet Gynecol 65:45S–48S 45. Tredal SM, Carter JB, Edwards JE (1974) Cystic medial necrosis of the pulmonary arteries: association with pulmonary hypertension. Arch Pathol 97:183–186 46. Niwa K, Perloff JK, Kaplan S et al (1999) Eisenmenger syndrome in adults: ventricular septal defect, truncus arteriosus, univentricular heart.

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Aortopathy by Koichiro Niwa, Harald Kaemmerer


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